Detection of activated lymphocytes in endocrine pancreas of BB/W rats by injection of 123I-interleukin-2: an early sign of type 1 diabetes.

Detection of activated lymphocytes in endocrine pancreas of BB/W rats by injection of 123I-interleukin-2: an early sign of type 1 diabetes.

Recombinant interleukin-2 (IL2) was labelled with iodine-123 by a modified chloramine T method. The labelled IL2, which had a high specific activity (100-150 microCi/microgram) and retained its capacity for binding to the IL2 receptor on activated lymphocytes in vitro, was injected intravenously int...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Signore, A, Parman, A, Pozzilli, P, Andreani, D, Beverley, P
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	1987

Eitemau Tebyg

Labelling of interleukin 2 with 123 iodine and its administration to animals susceptible to diabetes for the visualization of lymphocytic infiltration in the pancreas
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Cyhoeddwyd: (1988)

[Labelling of interleukin 2 with 123 iodine and its administration to animals susceptible to diabetes for the visualization of lymphocytic infiltration in the pancreas]
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Cyhoeddwyd: (1988)

Labelling of interleukin-2 (IL-2) with 123-iodine with retention of its capacity to bind to activated lymphocytes.
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