Heparan sulfate targets the HIV-1 envelope glycoprotein gp120 coreceptor binding site.

Human immunodeficiency virus (HIV) attachment to host cells is a multi-step process that involves interaction of the viral envelope gp120 with the primary receptor CD4 and coreceptors. HIV gp120 also binds to other cell surface components, including heparan sulfate (HS), a sulfated polysaccharide wh...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Vivès, R, Imberty, A, Sattentau, Q, Lortat-Jacob, H
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2005