MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.

MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.

The high level of 5-hydroxymethylcytosine (5hmC) present in neuronal genomes suggests that mechanisms interpreting 5hmC in the CNS may differ from those present in embryonic stem cells. Here, we present quantitative, genome-wide analysis of 5hmC, 5-methylcytosine (5mC), and gene expression in differ...

書誌詳細
主要な著者:	Mellén, M, Ayata, P, Dewell, S, Kriaucionis, S, Heintz, N
フォーマット:	Journal article
言語:	English
出版事項:	2012

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