Influence of HLA-C expression level on HIV control.

Influence of HLA-C expression level on HIV control.

A variant upstream of human leukocyte antigen C (HLA-C) shows the most significant genome-wide effect on HIV control in European Americans and is also associated with the level of HLA-C expression. We characterized the differential cell surface expression levels of all common HLA-C allotypes and tes...

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Hlavní autoři: Apps, R, Qi, Y, Carlson, J, Chen, H, Gao, X, Thomas, R, Yuki, Y, Del Prete, G, Goulder, P, Brumme, Z, Brumme, C, John, M, Mallal, S, Nelson, G, Bosch, R, Heckerman, D, Stein, J, Soderberg, K, Moody, M, Denny, T, Zeng, X, Fang, J, Moffett, A, Lifson, J, Goedert, J
Médium: Journal article
Jazyk:English
Vydáno: American Association for the Advancement of Science 2013

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