Influence of HLA-C expression level on HIV control.

A variant upstream of human leukocyte antigen C (HLA-C) shows the most significant genome-wide effect on HIV control in European Americans and is also associated with the level of HLA-C expression. We characterized the differential cell surface expression levels of all common HLA-C allotypes and tes...

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Detalles Bibliográficos
Autores principales: Apps, R, Qi, Y, Carlson, J, Chen, H, Gao, X, Thomas, R, Yuki, Y, Del Prete, G, Goulder, P, Brumme, Z, Brumme, C, John, M, Mallal, S, Nelson, G, Bosch, R, Heckerman, D, Stein, J, Soderberg, K, Moody, M, Denny, T, Zeng, X, Fang, J, Moffett, A, Lifson, J, Goedert, J
Formato: Journal article
Lenguaje:English
Publicado: American Association for the Advancement of Science 2013