Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study.

Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study.

OBJECTIVE: There is considerable interindividual variation in sulfonylurea response in type 2 diabetes. Transcription factor 7-like 2 (TCF7L2) variants have been identified to be strongly associated with type 2 diabetes risk, probably due to decreased beta-cell function. We hypothesized that variat...

Descripción completa

Detalles Bibliográficos
Autores principales: Pearson, E, Donnelly, L, Kimber, C, Whitley, A, Doney, A, McCarthy, M, Hattersley, A, Morris, A, Palmer, C
Formato: Journal article
Lenguaje:English
Publicado: 2007

Ejemplares similares

Ejemplares similares