Modelling the genetic aetiology of complex disease: human-mouse conservation of noncoding features and disease-associated loci
Understanding the genetic aetiology of loci associated with a disease is crucial for developing preventative measures and effective treatments. Mouse models are used extensively to understand human pathobiology and mechanistic functions of disease-associated loci. However, the utility of mouse model...
Main Authors: | Powell, G, Long, H, Zolkiewski, L, Dumbell, R, Mallon, A-M, Lindgren, CM, Simon, MM |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
Royal Society
2022
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