Modelling the genetic aetiology of complex disease: human-mouse conservation of noncoding features and disease-associated loci

Understanding the genetic aetiology of loci associated with a disease is crucial for developing preventative measures and effective treatments. Mouse models are used extensively to understand human pathobiology and mechanistic functions of disease-associated loci. However, the utility of mouse model...

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Hlavní autoři: Powell, G, Long, H, Zolkiewski, L, Dumbell, R, Mallon, A-M, Lindgren, CM, Simon, MM
Médium: Journal article
Jazyk:English
Vydáno: Royal Society 2022