Thymosin β4 mediates vascular protection via regulation of Low Density Lipoprotein Related Protein 1 (LRP1)

Vascular stability and tone are maintained by contractile smooth muscle cells (VSMCs). However, injury-induced growth factors stimulate a contractile-synthetic phenotypic switch which promotes atherosclerosis and susceptibility to abdominal aortic aneurysm (AAA). As a regulator of embryonic VSMC dif...

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Detalles Bibliográficos
Main Authors: Munshaw, S, Bruche, S, Patel, J, Redpath, A, Dube, KN, Davies, R, Neal, G, Lee, R, Handa, A, Channon, KM, Smart, N
Formato: Journal article
Idioma:English
Publicado: Cold Spring Harbor Laboratory 2019