A small amount of fat does not affect piperaquine exposure in patients with malaria.

Dihydroartemisinin-piperaquine is a new, highly effective, and well-tolerated combination treatment for uncomplicated falciparum malaria. The lipophilic characteristic of piperaquine suggests that administration together with fat will increase the oral bioavailability of the drug, and this has been...

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Détails bibliographiques
Auteurs principaux: Annerberg, A, Lwin, K, Lindegardh, N, Khrutsawadchai, S, Ashley, E, Day, N, Singhasivanon, P, Tarning, J, White, N, Nosten, F
Format: Journal article
Langue:English
Publié: 2011