Glucose analogue inhibitors of glycogen phosphorylase: the design of potential drugs for diabetes.

The T-state crystal structure of the glucose-phosphorylase b complex has been used as a model for the design of glucose analogue inhibitors that may be effective in the regulation of blood glucose levels. Modeling studies indicated room for additional atoms attached at the C1-beta position of glucos...

Celý popis

Podrobná bibliografie
Hlavní autoři: Martin, J, Veluraja, K, Ross, K, Johnson, L, Fleet, G, Ramsden, N, Bruce, I, Orchard, MG, Oikonomakos, N, Papageorgiou, A
Médium: Journal article
Jazyk:English
Vydáno: 1991