Glucose analogue inhibitors of glycogen phosphorylase: the design of potential drugs for diabetes.
The T-state crystal structure of the glucose-phosphorylase b complex has been used as a model for the design of glucose analogue inhibitors that may be effective in the regulation of blood glucose levels. Modeling studies indicated room for additional atoms attached at the C1-beta position of glucos...
| Główni autorzy: | , , , , , , , , , |
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| Format: | Journal article |
| Język: | English |
| Wydane: |
1991
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