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Chronic Creatine-deficiency is not the Underlying Cause of Cardiac Dysfunction in Mice Lacking the Creatine Biosynthetic Enzyme Arginine: glycine Amidinotransferase

Chronic Creatine-deficiency is not the Underlying Cause of Cardiac Dysfunction in Mice Lacking the Creatine Biosynthetic Enzyme Arginine: glycine Amidinotransferase

Dades bibliogràfiques
Autors principals: Lygate, C, Faller, K, Medway, D, Zervou, S, Choe, C, Isbrandt, D, Schneider, J, Neubauer, S
Format: Journal article
Publicat: 2013
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  • Cardiomyocytes from Creatine-Deficient Mice Lacking L-Arginine: Glycine Amidinotransferase (AGAT) Show No Changes in Mitochondrial Organization and Cellular Compartmentation
    per: Kotlyarova, S, et al.
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  • Arginine:Glycine Amidinotransferase Is Essential for Creatine Supply in Mice During Chronic Hypoxia
    per: Juliane Hannemann, et al.
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  • Impaired cardiac contractile function in AGAT knockout mice devoid of creatine is rescued by homoarginine but not creatine
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  • Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction.
    per: Lygate, C, et al.
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  • Creatine uptake in mouse hearts with genetically altered creatine levels.
    per: ten Hove, M, et al.
    Publicat: (2008)

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