Childhood bone mineral content is associated with methylation status of the RXRA promoter at birth.
Maternal vitamin D deficiency has been associated with reduced offspring bone mineral accrual. Retinoid-X receptor-alpha (RXRA) is an essential cofactor in the action of 1,25-dihydroxyvitamin D (1,25[OH]2 -vitamin D), and RXRA methylation in umbilical cord DNA has been associated with later offsprin...
Main Authors: | , , , , , , , , , , , , |
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Format: | Conference item |
Published: |
2014
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