Minimal in vivo efficacy of iminosugars in a lethal ebola virus guinea pig model
The antiviral properties of iminosugars have been reported previously in vitro and in small animal models against Ebola virus (EBOV); however, their effects have not been tested in larger animal models such as guinea pigs. We tested the iminosugars N-butyl-deoxynojirimycin (NB-DNJ) and N-(9- meth...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Journal article |
| Udgivet: |
Public Library of Science
2016
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