Content of health economics analysis plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey

Objectives Health economics analysis plans (HEAPs) currently lack consistency, with uncertainty surrounding appropriate content. We aimed to develop a list of essential items that should be included in HEAPs for economic evaluations conducted alongside randomized trials. Methods A list of potential...

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Hauptverfasser: Thorn, JC, Davies, CF, Brookes, ST, Noble, SM, Dritsaki, M, Gray, E, Hughes, DA, Mihaylova, B, Petrou, S, Ridyard, C, Sach, T, Wilson, ECF, Wordsworth, S, Hollingworth, W
Format: Journal article
Sprache:English
Veröffentlicht: Elsevier 2020
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author Thorn, JC
Davies, CF
Brookes, ST
Noble, SM
Dritsaki, M
Gray, E
Hughes, DA
Mihaylova, B
Petrou, S
Ridyard, C
Sach, T
Wilson, ECF
Wordsworth, S
Hollingworth, W
author_facet Thorn, JC
Davies, CF
Brookes, ST
Noble, SM
Dritsaki, M
Gray, E
Hughes, DA
Mihaylova, B
Petrou, S
Ridyard, C
Sach, T
Wilson, ECF
Wordsworth, S
Hollingworth, W
author_sort Thorn, JC
collection OXFORD
description Objectives Health economics analysis plans (HEAPs) currently lack consistency, with uncertainty surrounding appropriate content. We aimed to develop a list of essential items that should be included in HEAPs for economic evaluations conducted alongside randomized trials. Methods A list of potential items for inclusion was developed by examining existing HEAPs. An electronic Delphi survey was conducted among professional health economists. Respondents were asked to rate potential items from 1 (least important) to 9 (most important), suggest additional items, and comment on proposed items (round 1). A second survey (round 2) was emailed to participants, including the participant’s own scores from round 1 along with summary results from the whole panel; participants were asked to rerate each item. Consensus criteria for inclusion in the final list were predefined as >70% of participants rating an item 7-9 and <15% rating it 1-3 after round 2. A final item selection meeting was held to scrutinize the results and adjudicate on items lacking consensus. Results 62 participants completed round 1 of the survey. The initial list included 72 potential items; all 72 were carried forward to round 2, and no new items were added. 48 round 1 respondents (77.4%) completed round 2 and reached consensus on 53 items. At the final meeting, the expert panel (n = 9) agreed that 58 items should be included in the essential list, moved 9 items to an optional list, and dropped 5 items. Conclusions Via expert consensus opinion, this study identified 58 items that are considered essential in a HEAP.
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spelling oxford-uuid:9239ca68-22be-4147-9a87-8ceebad0c5562022-03-26T23:24:02ZContent of health economics analysis plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus surveyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9239ca68-22be-4147-9a87-8ceebad0c556EnglishSymplectic ElementsElsevier2020Thorn, JCDavies, CFBrookes, STNoble, SMDritsaki, MGray, EHughes, DAMihaylova, BPetrou, SRidyard, CSach, TWilson, ECFWordsworth, SHollingworth, WObjectives Health economics analysis plans (HEAPs) currently lack consistency, with uncertainty surrounding appropriate content. We aimed to develop a list of essential items that should be included in HEAPs for economic evaluations conducted alongside randomized trials. Methods A list of potential items for inclusion was developed by examining existing HEAPs. An electronic Delphi survey was conducted among professional health economists. Respondents were asked to rate potential items from 1 (least important) to 9 (most important), suggest additional items, and comment on proposed items (round 1). A second survey (round 2) was emailed to participants, including the participant’s own scores from round 1 along with summary results from the whole panel; participants were asked to rerate each item. Consensus criteria for inclusion in the final list were predefined as >70% of participants rating an item 7-9 and <15% rating it 1-3 after round 2. A final item selection meeting was held to scrutinize the results and adjudicate on items lacking consensus. Results 62 participants completed round 1 of the survey. The initial list included 72 potential items; all 72 were carried forward to round 2, and no new items were added. 48 round 1 respondents (77.4%) completed round 2 and reached consensus on 53 items. At the final meeting, the expert panel (n = 9) agreed that 58 items should be included in the essential list, moved 9 items to an optional list, and dropped 5 items. Conclusions Via expert consensus opinion, this study identified 58 items that are considered essential in a HEAP.
spellingShingle Thorn, JC
Davies, CF
Brookes, ST
Noble, SM
Dritsaki, M
Gray, E
Hughes, DA
Mihaylova, B
Petrou, S
Ridyard, C
Sach, T
Wilson, ECF
Wordsworth, S
Hollingworth, W
Content of health economics analysis plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey
title Content of health economics analysis plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey
title_full Content of health economics analysis plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey
title_fullStr Content of health economics analysis plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey
title_full_unstemmed Content of health economics analysis plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey
title_short Content of health economics analysis plans (HEAPs) for trial-based economic evaluations: expert Delphi consensus survey
title_sort content of health economics analysis plans heaps for trial based economic evaluations expert delphi consensus survey
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