Exploring the unknown: assumptions about allelic architecture and strategies for susceptibility variant discovery.

Identification of common-variant associations for many common disorders has been highly effective, but the loci detected so far typically explain only a small proportion of the genetic predisposition to disease. Extending explained genetic variance is one of the major near-term goals of human geneti...

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Detalhes bibliográficos
Autor principal: McCarthy, M
Formato: Journal article
Idioma:English
Publicado em: 2009