Reduced expression of molecules of the cadherin/catenin complex in the transition from colorectal adenoma to carcinoma.
E-cadherin is crucial to the intercellular adherens junctions which are involved in the organisation and maintenance of epithelial structure and suppression of tumour invasion. E-cadherin is associated with the actin cytoskeleton via cytoplasmic proteins, including alpha-, beta- and gamma-catenins,...
Auteurs principaux: | Hao, X, Palazzo, J, Ilyas, M, Tomlinson, I, Talbot, I |
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Format: | Journal article |
Langue: | English |
Publié: |
1997
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