Using CombiCells, a platform for titration and combinatorial display of cell surface ligands, to study T-cell antigen sensitivity modulation by accessory receptors

Using CombiCells, a platform for titration and combinatorial display of cell surface ligands, to study T-cell antigen sensitivity modulation by accessory receptors

Understanding how cellular decisions by receptor/ligand interactions at cell/cell interface has been challenging because it is difficult to independently vary the surface density of multiple ligands. Here, we exploit the SpyCatcher/SpyTag split-protein system for rapid combinatorial display of nativ...

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Bibliographic Details
Main Authors: Patel, A, André, V, Bustamante Eguiguren, S, Barton, MI, Burton, J, Denham, EM, Pettmann, J, Mørch, AM, Kutuzov, MA, Siller-Farfán, JA, Dustin, M, van der Merwe, PA, Dushek, O
Format: Journal article
Language:English
Published: EMBO Press 2023

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