Post-Ganglionic sympathetic neurons can directly sense raised extracellular Na+ via SCN7a/Nax

The relationship between dietary NaCl intake and high blood pressure is well-established, and occurs primarily through activation of the sympathetic nervous system. Nax, a Na+-sensitive Na+ channel, plays a pivotal role in driving sympathetic excitability, which is thought to originate from central...

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Bibliographic Details
Main Authors: Davis, H, Paterson, DJ, Herring, N
Format: Journal article
Language:English
Published: Frontiers Media 2022