Organization of chromosomal DNA by SMC complexes

Structural maintenance of chromosomes (SMC) complexes are key organizers of chromosome architecture in all kingdoms of life. Despite seemingly divergent functions, such as chromosome segregation, chromosome maintenance, sister chromatid cohesion, and mitotic chromosome compaction, it appears that th...

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Bibliografske podrobnosti
Main Authors: Yatskevich, S, Rhodes, J, Nasmyth, K
Format: Journal article
Jezik:English
Izdano: Annual Reviews 2019
Opis
Izvleček:Structural maintenance of chromosomes (SMC) complexes are key organizers of chromosome architecture in all kingdoms of life. Despite seemingly divergent functions, such as chromosome segregation, chromosome maintenance, sister chromatid cohesion, and mitotic chromosome compaction, it appears that these complexes function via highly conserved mechanisms and that they represent a novel class of DNA translocases.