Organization of chromosomal DNA by SMC complexes

Structural maintenance of chromosomes (SMC) complexes are key organizers of chromosome architecture in all kingdoms of life. Despite seemingly divergent functions, such as chromosome segregation, chromosome maintenance, sister chromatid cohesion, and mitotic chromosome compaction, it appears that th...

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Những tác giả chính: Yatskevich, S, Rhodes, J, Nasmyth, K
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Annual Reviews 2019
Miêu tả
Tóm tắt:Structural maintenance of chromosomes (SMC) complexes are key organizers of chromosome architecture in all kingdoms of life. Despite seemingly divergent functions, such as chromosome segregation, chromosome maintenance, sister chromatid cohesion, and mitotic chromosome compaction, it appears that these complexes function via highly conserved mechanisms and that they represent a novel class of DNA translocases.