Improved immunohistochemical detection of type 1 insulin-Like growth factor receptor in human tumors

Improved immunohistochemical detection of type 1 insulin-Like growth factor receptor in human tumors

<p><strong>Background:</strong> Insulin-like growth factors (IGFs) are known to play important roles in cancer biology, prompting evaluation of drugs targeting type 1 IGF receptor (IGF-1R). However, there is considerable lack of consensus in immunohistochemical (IHC) studies of IGF...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Macaulay, V, Aleksic, T, Turley, H, Worrall, A, Verrill, C, Campo, L
Định dạng:	Journal article
Được phát hành:	OMICS International Journals 2016

Những quyển sách tương tự

Type 1 insulin-like growth factor receptor translocates to the nucleus of human tumor cells.
Bằng: Aleksic, T, et al.
Được phát hành: (2010)

The type 1 insulin-like growth factor receptor pathway.
Bằng: Chitnis, M, et al.
Được phát hành: (2008)

Targeting the type 1 insulin-like growth factor receptor as a treatment for cancer.
Bằng: Yuen, J, et al.
Được phát hành: (2008)

Targeting the type 1 insulin-like growth factor receptor as anti-cancer treatment.
Bằng: Bohula, E, et al.
Được phát hành: (2003)

Insulin like growth factor receptor 1 (IGF-1R) and radiotherapy resistance in laryngeal squamous cell cancer (LSCC)
Bằng: Qureishi, A, et al.
Được phát hành: (2018)

The type 1 insulin-like growth factor receptor is over-expressed in bladder cancer.
Bằng: Rochester, M, et al.
Được phát hành: (2007)

Chemosensitization of human prostate cancer using antisense agents targeting the type 1 insulin-like growth factor receptor.
Bằng: Hellawell, G, et al.
Được phát hành: (2003)

Validation of the type 1 insulin-like growth factor receptor as a therapeutic target in renal cancer.
Bằng: Yuen, J, et al.
Được phát hành: (2009)

Validation of the type 1 insulin-like growth factor receptor as a therapeutic target in renal cancer
Bằng: Yuen, J, et al.
Được phát hành: (2009)

Silencing of the insulin receptor isoform A favors formation of type 1 insulin-like growth factor receptor (IGF-IR) homodimers and enhances ligand-induced IGF-IR activation and viability of human colon carcinoma cells.
Bằng: Brierley, G, et al.
Được phát hành: (2010)

Immunohistochemical detection of estrogen receptors in canine mammary tumors
Bằng: Elena Atanaskova Petrov, et al.
Được phát hành: (2016-03-01)

Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease.
Bằng: Hellawell, G, et al.
Được phát hành: (2002)

Activation of the insulin receptor by insulin-like growth factor 2
Bằng: Weidong An, et al.
Được phát hành: (2024-03-01)

Immunohistochemical detection of angiotensin receptors AT1 and AT2 in adrenal tumors.
Bằng: Marek Pawlikowski, et al.
Được phát hành: (2008-02-01)

Immunohistochemical detection of FSH receptors in pituitary adenomas and adrenal tumors
Bằng: Marek Pawlikowski, et al.
Được phát hành: (2012-10-01)

Phase I study of OSI-906, dual tyrosine kinase inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR) in combination with erlotinib (E) in patients with advanced solid tumors.
Bằng: Macaulay, V, et al.
Được phát hành: (2010)

Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase.
Bằng: Macaulay, V, et al.
Được phát hành: (2001)

The insulin-like growth factor system as a therapeutic target in colorectal cancer.
Bằng: Hassan, A, et al.
Được phát hành: (2002)

Mammary tumors that become independent of the type I insulin-like growth factor receptor express elevated levels of platelet-derived growth factor receptors
Bằng: Campbell Craig I, et al.
Được phát hành: (2011-11-01)

How ligand binds to the type 1 insulin-like growth factor receptor
Bằng: Yibin Xu, et al.
Được phát hành: (2018-02-01)

Type 1 insulin-like growth factor receptor inhibition as treatment for urological cancer
Bằng: Chitnis, M, et al.
Được phát hành: (2013)

Role of the Insulin-Like Growth Factor Type 1 Receptor in the Pathogenesis of Diabetic Encephalopathy
Bằng: Duo Zhang, et al.
Được phát hành: (2015-01-01)

Ligand-mediated Endocytosis and Trafficking of the Insulin-like Growth Factor Receptor I and Insulin Receptor Modulate Receptor Function
Bằng: Alaide eMorcavallo, et al.
Được phát hành: (2014-12-01)

Insulin-like growth factors: Ligands, binding proteins, and receptors
Bằng: Derek LeRoith, et al.
Được phát hành: (2021-10-01)

Insulin/insulin like growth factors in cancer: new roles for the aryl hydrocarbon receptor, tumor resistance mechanisms and new blocking strategies
Bằng: Travis B Salisbury, et al.
Được phát hành: (2015-02-01)

The efficacy of small interfering RNAs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF1R transcript.
Bằng: Bohula, E, et al.
Được phát hành: (2003)

Expression and cellular localization of vascular endothelial growth factor A and its receptors in acute and chronic leukemias: an immunohistochemical study.
Bằng: Zhang, Y, et al.
Được phát hành: (2005)

Insulin-Like Growth Factor Binding Protein-6 Promotes the Differentiation of Placental Mesenchymal Stem Cells into Skeletal Muscle Independent of Insulin-Like Growth Factor Receptor-1 and Insulin Receptor
Bằng: Doaa Aboalola, et al.
Được phát hành: (2019-01-01)

Bad to the bone: The role of the insulin-like growth factor axis in osseous metastasis
Bằng: Rieunier, G, et al.
Được phát hành: (2019)

Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin.
Bằng: Playford, M, et al.
Được phát hành: (2000)

Lectin-induced alterations of the interaction of insulin and insulin-like growth factor 1 receptors with their ligands
Bằng: ROMANA MASNIKOSA, et al.
Được phát hành: (2008-08-01)

Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II.
Bằng: Clair L Alvino, et al.
Được phát hành: (2011-01-01)

Extended silencing of the insulin-like growth factor-I receptor gene in MCF-7 cells by serial transfection with siRNA.
Bằng: McVittie, C, et al.
Được phát hành: (2006)

Genetic variation in the type 2 insulin-like growth factor receptor gene and disparity in childhood height.
Bằng: Petry, C, et al.
Được phát hành: (2005)

Immunohistochemical expression of estrogen receptors, progesterone receptors, and human epidermal growth-factor receptor 2/neu in epithelial ovarian tumors
Bằng: Zaineb Y Mohieldin, et al.
Được phát hành: (2022-01-01)

Immunohistochemical expression of Insulin-like growth factor-1, Transforming growth factor-beta1, and Vascular endothelial growth factor in parathyroid adenoma and hyperplasia
Bằng: Hamide Sayar, et al.
Được phát hành: (2014-01-01)

Direct integrin binding to insulin-like growth factor-2 through the C-domain is required for insulin-like growth factor receptor type 1 (IGF1R) signaling.
Bằng: Dora Maria Cedano Prieto, et al.
Được phát hành: (2017-01-01)

Insulin-like growth factor ligands, receptors, and binding proteins in cancer.
Bằng: Foulstone, E, et al.
Được phát hành: (2005)

Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection
Bằng: Ammaji Rajala, et al.
Được phát hành: (2022-07-01)

Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes
Bằng: Kim Moorwood, et al.
Được phát hành: (2024-05-01)