Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

Protein synthesis in mammalian cells requires initiation factor eIF3, an approximately 800-kDa protein complex that plays a central role in binding of initiator methionyl-tRNA and mRNA to the 40 S ribosomal subunit to form the 48 S initiation complex. The eIF3 complex also prevents premature associa...

书目详细资料
Main Authors:	Damoc, E, Fraser, C, Zhou, M, Videler, H, Mayeur, G, Hershey, J, Doudna, J, Robinson, C, Leary, J
格式:	Journal article
语言:	English
出版:	2007

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