Optimising cell aggregate expansion in a perfused hollow fibre bioreactor via mathematical modelling

Optimising cell aggregate expansion in a perfused hollow fibre bioreactor via mathematical modelling

The need for efficient and controlled expansion of cell populations is paramount in tissue engineering. Hollow fibre bioreactors (HFBs) have the potential to meet this need, but only with improved understanding of how operating conditions and cell seeding strategy affect cell proliferation in the bi...

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Autors principals:	Chapman, L, Shipley, R, Whiteley, J, Ellis, M, Byrne, H, Waters, S
Format:	Journal article
Publicat:	Public Library of Science 2014

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