Optimising cell aggregate expansion in a perfused hollow fibre bioreactor via mathematical modelling
The need for efficient and controlled expansion of cell populations is paramount in tissue engineering. Hollow fibre bioreactors (HFBs) have the potential to meet this need, but only with improved understanding of how operating conditions and cell seeding strategy affect cell proliferation in the bi...
| Autori principali: | , , , , , |
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| Natura: | Journal article |
| Pubblicazione: |
Public Library of Science
2014
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