Optimising cell aggregate expansion in a perfused hollow fibre bioreactor via mathematical modelling

The need for efficient and controlled expansion of cell populations is paramount in tissue engineering. Hollow fibre bioreactors (HFBs) have the potential to meet this need, but only with improved understanding of how operating conditions and cell seeding strategy affect cell proliferation in the bi...

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Những tác giả chính: Chapman, L, Shipley, R, Whiteley, J, Ellis, M, Byrne, H, Waters, S
Định dạng: Journal article
Được phát hành: Public Library of Science 2014