Age-dependent changes in protein incorporation into collagen-rich tissues of mice by in vivo pulsed SILAC labelling

Collagen-rich tissues have poor reparative capacity that predisposes to common age-related disorders such as osteoporosis and osteoarthritis. We used in vivo pulsed SILAC labelling to quantify new protein incorporation into cartilage, bone, and skin of mice across the healthy life course. We report...

ver descrição completa

Detalhes bibliográficos
Main Authors: Ariosa-Morejon, Y, Santos, A, Fischer, R, Davis, S, Charles, P, Thakker, R, Wann, A, Vincent, TL
Formato: Journal article
Idioma:English
Publicado em: eLife Sciences Publications 2021