Neuroleptic malignant-like syndrome after abrupt withdrawal of baclofen.
We present the case of a 36-year-old man who presented with a clinically neuroleptic malignant-like syndrome involving disorientation, signs of autonomic dysfunction, rigidity and raised total creatine kinase level, but in the absence of any neuroleptic medication. He had, however, abruptly stopped...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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2001
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| _version_ | 1797082499454599168 |
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| author | Turner, M Gainsborough, N |
| author_facet | Turner, M Gainsborough, N |
| author_sort | Turner, M |
| collection | OXFORD |
| description | We present the case of a 36-year-old man who presented with a clinically neuroleptic malignant-like syndrome involving disorientation, signs of autonomic dysfunction, rigidity and raised total creatine kinase level, but in the absence of any neuroleptic medication. He had, however, abruptly stopped taking his long-term baclofen in the days prior to presentation. He improved markedly after the reintroduction of baclofen, and we postulate that his clinical syndrome resulted from the sudden withdrawal of this drug. We concur with the concept that neuroleptic malignant syndrome represents a spectrum of disorders, and add it to the list of possible sequelae after abrupt withdrawal of baclofen. |
| first_indexed | 2024-03-07T01:28:49Z |
| format | Journal article |
| id | oxford-uuid:92e561d6-f3ea-42b0-aad9-42fbb48e3a49 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:28:49Z |
| publishDate | 2001 |
| record_format | dspace |
| spelling | oxford-uuid:92e561d6-f3ea-42b0-aad9-42fbb48e3a492022-03-26T23:28:39ZNeuroleptic malignant-like syndrome after abrupt withdrawal of baclofen.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:92e561d6-f3ea-42b0-aad9-42fbb48e3a49EnglishSymplectic Elements at Oxford2001Turner, MGainsborough, NWe present the case of a 36-year-old man who presented with a clinically neuroleptic malignant-like syndrome involving disorientation, signs of autonomic dysfunction, rigidity and raised total creatine kinase level, but in the absence of any neuroleptic medication. He had, however, abruptly stopped taking his long-term baclofen in the days prior to presentation. He improved markedly after the reintroduction of baclofen, and we postulate that his clinical syndrome resulted from the sudden withdrawal of this drug. We concur with the concept that neuroleptic malignant syndrome represents a spectrum of disorders, and add it to the list of possible sequelae after abrupt withdrawal of baclofen. |
| spellingShingle | Turner, M Gainsborough, N Neuroleptic malignant-like syndrome after abrupt withdrawal of baclofen. |
| title | Neuroleptic malignant-like syndrome after abrupt withdrawal of baclofen. |
| title_full | Neuroleptic malignant-like syndrome after abrupt withdrawal of baclofen. |
| title_fullStr | Neuroleptic malignant-like syndrome after abrupt withdrawal of baclofen. |
| title_full_unstemmed | Neuroleptic malignant-like syndrome after abrupt withdrawal of baclofen. |
| title_short | Neuroleptic malignant-like syndrome after abrupt withdrawal of baclofen. |
| title_sort | neuroleptic malignant like syndrome after abrupt withdrawal of baclofen |
| work_keys_str_mv | AT turnerm neurolepticmalignantlikesyndromeafterabruptwithdrawalofbaclofen AT gainsboroughn neurolepticmalignantlikesyndromeafterabruptwithdrawalofbaclofen |