The role of loop stacking in the dynamics of DNA hairpin formation.

We study the dynamics of DNA hairpin formation using oxDNA, a nucleotide-level coarse-grained model of DNA. In particular, we explore the effects of the loop stacking interactions and non-native base pairing on the hairpin closing times. We find a nonmonotonic variation of the hairpin closing time w...

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Hlavní autoři: Mosayebi, M, Romano, F, Ouldridge, T, Louis, A, Doye, J
Médium: Journal article
Jazyk:English
Vydáno: American Chemical Society 2014