Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses.
Natural killer (NK) cells directly lyse tumor or viral-infected cells but also an important role for NK cell cytotoxicity in regulating the extent of immune responses is emerging. Here, we show that autologous human macrophages activated NK cell proliferation and cytokine secretion, increased expres...
Main Authors: | Nedvetzki, S, Sowinski, S, Eagle, R, Harris, J, Vély, F, Pende, D, Trowsdale, J, Vivier, E, Gordon, S, Davis, D |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2007
|
Similar Items
-
The role of the cytoskeleton and protein size in assembly of the human natural killer cell immune synapse
by: McCann, F, et al.
Published: (2003) -
Intercellular transfer and supramolecular organization of human leukocyte antigen C at inhibitory natural killer cell immune synapses.
by: Carlin, L, et al.
Published: (2001) -
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy
by: Brown, A, et al.
Published: (2011) -
Natural Killer Cells and Anti-Cancer Therapies: Reciprocal Effects on Immune Function and Therapeutic Response
by: Elisa C. Toffoli, et al.
Published: (2021-02-01) -
Centriole polarisation to the immunological synapse directs secretion from cytolytic cells of both the innate and adaptive immune systems.
by: Stinchcombe, J, et al.
Published: (2011)