An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation.

A T helper cell type 1-mediated colitis develops in severe combined immunodeficient mice after transfer of CD45RB(high) CD4(+) T cells and can be prevented by cotransfer of the CD45RB(low) subset. The immune-suppressive activities of the CD45RB(low) T cell population can be reversed in vivo by admin...

詳細記述

書誌詳細
主要な著者: Asseman, C, Mauze, S, Leach, M, Coffman, R, Powrie, F
フォーマット: Journal article
言語:English
出版事項: 1999