The parasitic lifestyle of an archaeal symbiont
DPANN archaea are a diverse group of microorganisms characterised by small cells and reduced genomes. To date, all cultivated DPANN archaea are ectosymbionts that require direct cell contact with an archaeal host species for growth and survival. However, these interactions and their impact on the ho...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Nature Research
2024
|
| _version_ | 1826313803529191424 |
|---|---|
| author | Hamm, JN Liao, Y von Kügelgen, A Dombrowski, N Landers, E Brownlee, C Johansson, EMV Whan, RM Baker, MAB Baum, B Bharat, TAM Duggin, IG Spang, A Cavicchioli, R |
| author_facet | Hamm, JN Liao, Y von Kügelgen, A Dombrowski, N Landers, E Brownlee, C Johansson, EMV Whan, RM Baker, MAB Baum, B Bharat, TAM Duggin, IG Spang, A Cavicchioli, R |
| author_sort | Hamm, JN |
| collection | OXFORD |
| description | DPANN archaea are a diverse group of microorganisms characterised by small cells and reduced genomes. To date, all cultivated DPANN archaea are ectosymbionts that require direct cell contact with an archaeal host species for growth and survival. However, these interactions and their impact on the host species are poorly understood. Here, we show that a DPANN archaeon (Candidatus Nanohaloarchaeum antarcticus) engages in parasitic interactions with its host (Halorubrum lacusprofundi) that result in host cell lysis. During these interactions, the nanohaloarchaeon appears to enter, or be engulfed by, the host cell. Our results provide experimental evidence for a predatory-like lifestyle of an archaeon, suggesting that at least some DPANN archaea may have roles in controlling host populations and their ecology. |
| first_indexed | 2024-09-25T04:22:20Z |
| format | Journal article |
| id | oxford-uuid:9341233b-07b6-4bd6-bfec-c01faadf339d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-09-25T04:22:20Z |
| publishDate | 2024 |
| publisher | Nature Research |
| record_format | dspace |
| spelling | oxford-uuid:9341233b-07b6-4bd6-bfec-c01faadf339d2024-08-10T19:33:45ZThe parasitic lifestyle of an archaeal symbiontJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9341233b-07b6-4bd6-bfec-c01faadf339dEnglishJisc Publications RouterNature Research2024Hamm, JNLiao, Yvon Kügelgen, ADombrowski, NLanders, EBrownlee, CJohansson, EMVWhan, RMBaker, MABBaum, BBharat, TAMDuggin, IGSpang, ACavicchioli, RDPANN archaea are a diverse group of microorganisms characterised by small cells and reduced genomes. To date, all cultivated DPANN archaea are ectosymbionts that require direct cell contact with an archaeal host species for growth and survival. However, these interactions and their impact on the host species are poorly understood. Here, we show that a DPANN archaeon (Candidatus Nanohaloarchaeum antarcticus) engages in parasitic interactions with its host (Halorubrum lacusprofundi) that result in host cell lysis. During these interactions, the nanohaloarchaeon appears to enter, or be engulfed by, the host cell. Our results provide experimental evidence for a predatory-like lifestyle of an archaeon, suggesting that at least some DPANN archaea may have roles in controlling host populations and their ecology. |
| spellingShingle | Hamm, JN Liao, Y von Kügelgen, A Dombrowski, N Landers, E Brownlee, C Johansson, EMV Whan, RM Baker, MAB Baum, B Bharat, TAM Duggin, IG Spang, A Cavicchioli, R The parasitic lifestyle of an archaeal symbiont |
| title | The parasitic lifestyle of an archaeal symbiont |
| title_full | The parasitic lifestyle of an archaeal symbiont |
| title_fullStr | The parasitic lifestyle of an archaeal symbiont |
| title_full_unstemmed | The parasitic lifestyle of an archaeal symbiont |
| title_short | The parasitic lifestyle of an archaeal symbiont |
| title_sort | parasitic lifestyle of an archaeal symbiont |
| work_keys_str_mv | AT hammjn theparasiticlifestyleofanarchaealsymbiont AT liaoy theparasiticlifestyleofanarchaealsymbiont AT vonkugelgena theparasiticlifestyleofanarchaealsymbiont AT dombrowskin theparasiticlifestyleofanarchaealsymbiont AT landerse theparasiticlifestyleofanarchaealsymbiont AT brownleec theparasiticlifestyleofanarchaealsymbiont AT johanssonemv theparasiticlifestyleofanarchaealsymbiont AT whanrm theparasiticlifestyleofanarchaealsymbiont AT bakermab theparasiticlifestyleofanarchaealsymbiont AT baumb theparasiticlifestyleofanarchaealsymbiont AT bharattam theparasiticlifestyleofanarchaealsymbiont AT dugginig theparasiticlifestyleofanarchaealsymbiont AT spanga theparasiticlifestyleofanarchaealsymbiont AT cavicchiolir theparasiticlifestyleofanarchaealsymbiont AT hammjn parasiticlifestyleofanarchaealsymbiont AT liaoy parasiticlifestyleofanarchaealsymbiont AT vonkugelgena parasiticlifestyleofanarchaealsymbiont AT dombrowskin parasiticlifestyleofanarchaealsymbiont AT landerse parasiticlifestyleofanarchaealsymbiont AT brownleec parasiticlifestyleofanarchaealsymbiont AT johanssonemv parasiticlifestyleofanarchaealsymbiont AT whanrm parasiticlifestyleofanarchaealsymbiont AT bakermab parasiticlifestyleofanarchaealsymbiont AT baumb parasiticlifestyleofanarchaealsymbiont AT bharattam parasiticlifestyleofanarchaealsymbiont AT dugginig parasiticlifestyleofanarchaealsymbiont AT spanga parasiticlifestyleofanarchaealsymbiont AT cavicchiolir parasiticlifestyleofanarchaealsymbiont |