Enzyme kinetics at high enzyme concentrations

We re-visit previous analyses of the classical Michaelis-Menten substrate-enzyme reaction and, with the aid of the reverse quasi-steady-state assumption, we challenge the approximation d[C]/dt ≈ 0 for the basic enzyme reaction at high enzyme concentration. For the first time, an approximate solution...

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Bibliographic Details
Main Authors: Schnell, S, Maini, P
Format: Journal article
Published: 2000

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