The effects of Hill-Robertson interference between weakly selected mutations on patterns of molecular evolution and variation.
Associations between selected alleles and the genetic backgrounds on which they are found can reduce the efficacy of selection. We consider the extent to which such interference, known as the Hill-Robertson effect, acting between weakly selected alleles, can restrict molecular adaptation and affect...
Main Authors: | Mcvean, G, Charlesworth, B |
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Format: | Journal article |
Language: | English |
Published: |
2000
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