Effects of drinking on late-life brain and cognition

Alcohol consumption is common in Western countries and has been increasing in older adults. Latest figures from Great Britain suggest 75% of those over 65 years drink, an increase from 71% 10 years ago. Chronic heavy intake is a well-established cause of brain atrophy and dementia, with a recent lon...

Full description

Bibliographic Details
Main Authors: Topiwala, A, Ebmeier, K
Format: Journal article
Language:English
Published: BMJ Publishing Group 2017
_version_ 1797082629236850688
author Topiwala, A
Ebmeier, K
author_facet Topiwala, A
Ebmeier, K
author_sort Topiwala, A
collection OXFORD
description Alcohol consumption is common in Western countries and has been increasing in older adults. Latest figures from Great Britain suggest 75% of those over 65 years drink, an increase from 71% 10 years ago. Chronic heavy intake is a well-established cause of brain atrophy and dementia, with a recent long-term prospective study from the USA reporting a doubling of the odds of later severe memory impairment in those with a history of an alcohol use disorder. Drinking of moderate amounts has been reported to be protective for brain health in a number of epidemiological studies, including some claims of possibly reducing dementia risk. Rigorous recent research has questioned this belief, with new evidence of harmful associations in moderate drinkers compared with abstainers. This has raised suspicion that reported protective effects of moderate drinking were due to confounding by socioeconomic class and intelligence. Clinicians should look out for cognitive impairment in heavy drinkers, considering that abstinence may induce a degree of clinical improvement. Discussions with patients regarding moderate drinking should be informed by recent research. Health benefits of moderate drinking at least for cognitive function are questionable, and if they exist are probably limited to one unit of alcohol daily with respect to other body systems.
first_indexed 2024-03-07T01:30:25Z
format Journal article
id oxford-uuid:936a3c0c-df2c-4303-89b4-369dc704efbc
institution University of Oxford
language English
last_indexed 2024-03-07T01:30:25Z
publishDate 2017
publisher BMJ Publishing Group
record_format dspace
spelling oxford-uuid:936a3c0c-df2c-4303-89b4-369dc704efbc2022-03-26T23:32:05ZEffects of drinking on late-life brain and cognitionJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:936a3c0c-df2c-4303-89b4-369dc704efbcEnglishSymplectic Elements at OxfordBMJ Publishing Group2017Topiwala, AEbmeier, KAlcohol consumption is common in Western countries and has been increasing in older adults. Latest figures from Great Britain suggest 75% of those over 65 years drink, an increase from 71% 10 years ago. Chronic heavy intake is a well-established cause of brain atrophy and dementia, with a recent long-term prospective study from the USA reporting a doubling of the odds of later severe memory impairment in those with a history of an alcohol use disorder. Drinking of moderate amounts has been reported to be protective for brain health in a number of epidemiological studies, including some claims of possibly reducing dementia risk. Rigorous recent research has questioned this belief, with new evidence of harmful associations in moderate drinkers compared with abstainers. This has raised suspicion that reported protective effects of moderate drinking were due to confounding by socioeconomic class and intelligence. Clinicians should look out for cognitive impairment in heavy drinkers, considering that abstinence may induce a degree of clinical improvement. Discussions with patients regarding moderate drinking should be informed by recent research. Health benefits of moderate drinking at least for cognitive function are questionable, and if they exist are probably limited to one unit of alcohol daily with respect to other body systems.
spellingShingle Topiwala, A
Ebmeier, K
Effects of drinking on late-life brain and cognition
title Effects of drinking on late-life brain and cognition
title_full Effects of drinking on late-life brain and cognition
title_fullStr Effects of drinking on late-life brain and cognition
title_full_unstemmed Effects of drinking on late-life brain and cognition
title_short Effects of drinking on late-life brain and cognition
title_sort effects of drinking on late life brain and cognition
work_keys_str_mv AT topiwalaa effectsofdrinkingonlatelifebrainandcognition
AT ebmeierk effectsofdrinkingonlatelifebrainandcognition