Approaches for establishing the function of regulatory genetic variants involved in disease.
The diversity of regulatory genetic variants and their mechanisms of action reflect the complexity and context-specificity of gene regulation. Regulatory variants are important in human disease and defining such variants and establishing mechanism is crucial to the interpretation of disease-associat...
Main Author: | Knight, J |
---|---|
Format: | Journal article |
Language: | English |
Published: |
BioMed Central
2014
|
Similar Items
-
Translating GWAS in rheumatic disease: approaches to establishing mechanism and function for genetic associations with ankylosing spondylitis
by: Osgood, J, et al.
Published: (2018) -
Genetic Variant Overlap Analysis Identifies Established and Putative Genes Involved in Pulmonary Fibrosis
by: Karlijn Groen, et al.
Published: (2023-02-01) -
Dissecting the gene-regulatory circuitry of disease-associated genetic variants
by: Herr, Taylor(Taylor J.)
Published: (2020) -
Identification of regulatory variants associated with genetic susceptibility to meningococcal disease
by: Borghini, L, et al.
Published: (2019) -
Genetic, functional, and phenotypic analysis of human variants in the glucokinase regulatory protein gene
by: Rees, M, et al.
Published: (2012)