RNA in defense: CRISPRs protect prokaryotes against mobile genetic elements

RNA in defense: CRISPRs protect prokaryotes against mobile genetic elements

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The CRISPR/Cas system in prokaryotes provides resistance against invading viruses and plasmids. Three distinct stages in the mechanism can be recognized. Initially, fragments of invader DNAare integrated as newspacers into the repetitive CRISPR locus. Subsequently, the CRISPR is transcribed and the...

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Dettagli Bibliografici
Autori principali:	Jore, M, Brouns, S, van der Oost, J
Natura:	Journal article
Lingua:	English
Pubblicazione:	2012

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