Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila.

The membrane proteins Star and Rhomboid-1 have been genetically defined as the primary regulators of EGF receptor activation in Drosophila, but their molecular mechanisms have been elusive. Both Star and Rhomboid-1 have been assumed to work at the cell surface to control ligand activation. Here, we...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Lee, JR, Urban, S, Garvey, C, Freeman, M
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2001