Regulatory T cells can prevent memory CD8+ T-cell-mediated rejection following polymorphonuclear cell depletion.
Accumulating evidence suggests that alloreactive memory T cells (Tm) may form a barrier to tolerance induction in large animals and humans due in part to a resistance to suppression by Treg. However, why Tm are resistant to regulation and how the Tm response to an allograft differs from that of naïv...
Автори: | Jones, N, Brook, M, Carvalho-Gaspar, M, Luo, S, Wood, K |
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Формат: | Journal article |
Мова: | English |
Опубліковано: |
2010
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