Tissue, cell and stage specificity of (epi)mutations in cancers.
Most (epi)mutations in cancers are specific to particular tumours or occur at specific stages of development, cell differentiation or tumorigenesis. Simple molecular mechanisms, such as tissue-restricted gene expression, seem to explain these associations only in rare cases. Instead, the specificity...
Main Authors: | Sieber, O, Tomlinson, SR, Tomlinson, I |
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Format: | Journal article |
Language: | English |
Published: |
2005
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