MacB ABC transporter is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA.

MacB ABC transporter is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA.

Gram-negative bacteria utilize specialized machinery to translocate drugs and protein toxins across the inner and outer membranes, consisting of a tripartite complex composed of an inner membrane secondary or primary active transporter (IMP), a periplasmic membrane fusion protein, and an outer membr...

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Bibliographic Details
Main Authors: Lin, H, Bavro, V, Barrera, N, Frankish, H, Velamakanni, S, van Veen, H, Robinson, C, Borges-Walmsley, M, Walmsley, A
Format: Journal article
Language:English
Published: 2009

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