Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes.

Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes.

Several common genetic variations have been associated with type 2 diabetes, but the exact disease mechanisms are still poorly elucidated. Using congenic strains from the diabetic Goto-Kakizaki rat, we identified a 1.4-megabase genomic locus that was linked to impaired insulin granule docking at the...

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Bibliographic Details
Main Authors:	Rosengren, A, Jokubka, R, Tojjar, D, Granhall, C, Hansson, O, Li, D, Nagaraj, V, Reinbothe, T, Tuncel, J, Eliasson, L, Groop, L, Rorsman, P, Salehi, A, Lyssenko, V, Luthman, H, Renström, E
Format:	Journal article
Language:	English
Published:	2010

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