Lack of hexose-6-phosphate dehydrogenase impairs lipid mobilization from mouse adipose tissue.

Lack of hexose-6-phosphate dehydrogenase impairs lipid mobilization from mouse adipose tissue.

In adipose tissue, glucocorticoids regulate lipogenesis and lipolysis. Hexose-6-phosphate dehydrogenase (H6PDH) is an enzyme located in the endoplasmic reticulum that provides a cofactor for the enzyme 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1), regulating the set point of its activity...

Descripció completa

Dades bibliogràfiques
Autors principals:	Bujalska, I, Hewitt, K, Hauton, D, Lavery, G, Tomlinson, J, Walker, E, Stewart, P
Format:	Journal article
Idioma:	English
Publicat:	2008

Ítems similars

Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1.
per: Bujalska, I, et al.
Publicat: (2005)

Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency.
per: Draper, N, et al.
Publicat: (2003)

Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency.
per: Lavery, G, et al.
Publicat: (2008)

An autosomal glucose-6-phosphate dehydrogenase (hexose-6-phosphate dehydrogenase) polymorphism in human saliva
per: Tan, Soon Guan, et al.
Publicat: (1976)

Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue
per: Gathercole, L, et al.
Publicat: (2011)

Glucocorticoid and insulin regulation of lipogenesis in human adipose tissue
per: Gathercole, L, et al.
Publicat: (2010)

Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis.
per: Alcina, A, et al.
Publicat: (2010)

Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity.
per: Tomlinson, J, et al.
Publicat: (2002)

Genotype at the P554L variant of the hexose-6 phosphate dehydrogenase gene is associated with carotid intima-medial thickness
per: Rahman, T, et al.
Publicat: (2011)

Genotype at the P554L variant of the hexose-6 phosphate dehydrogenase gene is associated with carotid intima-medial thickness.
per: Rahman, T, et al.
Publicat: (2011)

11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response.
per: Tomlinson, J, et al.
Publicat: (2004)

Regulation of expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue: tissue-specific induction by cytokines.
per: Tomlinson, J, et al.
Publicat: (2001)

The functional consequences of 11beta-hydroxysteroid dehydrogenase expression in adipose tissue.
per: Tomlinson, J, et al.
Publicat: (2002)

Androgen generation in adipose tissue in women with simple obesity--a site-specific role for 17beta-hydroxysteroid dehydrogenase type 5.
per: Quinkler, M, et al.
Publicat: (2004)

Characterisation of 11beta-hydroxysteroid dehydrogenase 1 in human orbital adipose tissue: a comparison with subcutaneous and omental fat.
per: Bujalska, I, et al.
Publicat: (2007)

Glucocorticoid modulation of insulin signaling in human subcutaneous adipose tissue.
per: Gathercole, L, et al.
Publicat: (2007)

Glucocorticoid and Insulin Regulation of Lipogenesis in Human Adipose Tissue.
per: Gathercole, L, et al.
Publicat: (2010)

The role of 11 beta-hydroxysteroid dehydrogenase in central obesity and osteoporosis.
per: Tomlinson, J, et al.
Publicat: (2000)

Short- and long-term glucocorticoid treatment enhances insulin signalling in human subcutaneous adipose tissue.
per: Gathercole, L, et al.
Publicat: (2011)

Depot-specific prostaglandin synthesis in human adipose tissue: a novel possible mechanism of adipogenesis.
per: Quinkler, M, et al.
Publicat: (2006)

11Beta-hydroxysteroid dehydrogenase type 1 in differentiating omental human preadipocytes: from de-activation to generation of cortisol.
per: Bujalska, I, et al.
Publicat: (2002)

Weight loss increases 11beta-hydroxysteroid dehydrogenase type 1 expression in human adipose tissue.
per: Tomlinson, J, et al.
Publicat: (2004)

Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1.
per: Lavery, G, et al.
Publicat: (2012)

Hexose phosphorylation for a non-enzymatic glycolysis and pentose phosphate pathway on early Earth
per: Yuta Hirakawa, et al.
Publicat: (2024-01-01)

11beta-Hydroxysteroid dehydrogenase type 1 regulates insulin and glucagon secretion in pancreatic islets.
per: Swali, A, et al.
Publicat: (2008)

Studies on glyceraldehyde 3 phosphate dehydrogenase
per: Clark-Walker, G
Publicat: (1965)

Elevated Hexose-6-Phosphate Dehydrogenase Regulated by OSMR-AS1/hsa-miR-516b-5p Axis Correlates with Poor Prognosis and Dendritic Cells Infiltration of Glioblastoma
per: Yi-Bin Zhang, et al.
Publicat: (2022-07-01)

Fructose 2,6-bisphosphate activates pyrophosphate: fructose-6-phosphate 1-phosphotransferase and increases triose phosphate to hexose phosphate cycling in heterotrophic cells.
per: Fernie, A, et al.
Publicat: (2001)

Acute hypercortisolemia exerts depot-specific effects on abdominal and femoral adipose tissue function.
per: Manolopoulos, K, et al.
Publicat: (2017)

The role of 11beta-hydroxysteroid dehydrogenase 1 in adipogenesis in thyroid-associated ophthalmopathy.
per: Tomlinson, J, et al.
Publicat: (2010)

Expression profiling of 11beta-hydroxysteroid dehydrogenase type-1 and glucocorticoid-target genes in subcutaneous and omental human preadipocytes.
per: Bujalska, I, et al.
Publicat: (2006)

Impaired glucose tolerance and insulin resistance are associated with increased adipose 11beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity.
per: Tomlinson, J, et al.
Publicat: (2008)

Correction: On the Evolution of Hexose Transporters in Kinetoplastid Potozoans
Publicat: (2012-01-01)

Correction: On the Evolution of Hexose Transporters in Kinetoplastid Potozoans.
per: Claudio Alejandro Pereira, et al.
Publicat: (2012-01-01)

The Hexose efflux from the peeled grape berry
per: Predrag Nenad Božović, et al.
Publicat: (2019-05-01)

On the evolution of hexose transporters in kinetoplastid Protozoans [corrected].
per: Claudio Alejandro Pereira, et al.
Publicat: (2012-01-01)

Increased central adiposity and decreased subcutaneous adipose tissue 11β‐hydroxysteroid dehydrogenase type 1 are associated with deterioration in glucose tolerance—A longitudinal cohort study
per: Crowley, R, et al.
Publicat: (2019)

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 activity in vivo limits glucocorticoid exposure to human adipose tissue and decreases lipolysis.
per: Tomlinson, J, et al.
Publicat: (2007)

11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects.
per: Gathercole, L, et al.
Publicat: (2013)

MRS reveals additional hexose N-acetyl resonances in the brain of a mouse model for Sandhoff disease.
per: Lowe, J, et al.
Publicat: (2005)