Lack of hexose-6-phosphate dehydrogenase impairs lipid mobilization from mouse adipose tissue.
In adipose tissue, glucocorticoids regulate lipogenesis and lipolysis. Hexose-6-phosphate dehydrogenase (H6PDH) is an enzyme located in the endoplasmic reticulum that provides a cofactor for the enzyme 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1), regulating the set point of its activity...
Κύριοι συγγραφείς: | Bujalska, I, Hewitt, K, Hauton, D, Lavery, G, Tomlinson, J, Walker, E, Stewart, P |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2008
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency.
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Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue
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