Lack of hexose-6-phosphate dehydrogenase impairs lipid mobilization from mouse adipose tissue.

Lack of hexose-6-phosphate dehydrogenase impairs lipid mobilization from mouse adipose tissue.

In adipose tissue, glucocorticoids regulate lipogenesis and lipolysis. Hexose-6-phosphate dehydrogenase (H6PDH) is an enzyme located in the endoplasmic reticulum that provides a cofactor for the enzyme 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1), regulating the set point of its activity...

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Détails bibliographiques
Auteurs principaux:	Bujalska, I, Hewitt, K, Hauton, D, Lavery, G, Tomlinson, J, Walker, E, Stewart, P
Format:	Journal article
Langue:	English
Publié:	2008

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