Lack of hexose-6-phosphate dehydrogenase impairs lipid mobilization from mouse adipose tissue.
In adipose tissue, glucocorticoids regulate lipogenesis and lipolysis. Hexose-6-phosphate dehydrogenase (H6PDH) is an enzyme located in the endoplasmic reticulum that provides a cofactor for the enzyme 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1), regulating the set point of its activity...
Main Authors: | Bujalska, I, Hewitt, K, Hauton, D, Lavery, G, Tomlinson, J, Walker, E, Stewart, P |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado: |
2008
|
Títulos similares
-
Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1.
por: Bujalska, I, et al.
Publicado: (2005) -
Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency.
por: Draper, N, et al.
Publicado: (2003) -
Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency.
por: Lavery, G, et al.
Publicado: (2008) -
An autosomal glucose-6-phosphate dehydrogenase (hexose-6-phosphate dehydrogenase) polymorphism in human saliva
por: Tan, Soon Guan, et al.
Publicado: (1976) -
Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue
por: Gathercole, L, et al.
Publicado: (2011)