Analysis of giant cell tumour of bone cells for Noonan syndrome/cherubism-related mutations.
BACKGROUND: Giant cell tumour of bone (GCTB) is an osteolytic tumour which contains numerous osteoclast-like giant cells and a proliferation of mononuclear stromal cells (MSC). Giant cell-rich osteolytic lesions can also develop in the jaw bones in Noonan syndrome, a cherubism-like developmental abn...
Principais autores: | , , , , , |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
2013
|