A New Vaccine for Tuberculosis: The Challenges of Development and Deployment

Tuberculosis (TB) is one of the world's leading causes of death due to infection and efforts to control TB would be substantially aided by the availability of an improved TB vaccine. There are currently nine new TB vaccines in clinical development, and the first efficacy trials are due to comme...

Full description

Bibliographic Details
Main Authors: Fletcher, H, Hawkridge, T, Mcshane, H
Format: Journal article
Language:English
Published: 2009
_version_ 1797082751481937920
author Fletcher, H
Hawkridge, T
Mcshane, H
author_facet Fletcher, H
Hawkridge, T
Mcshane, H
author_sort Fletcher, H
collection OXFORD
description Tuberculosis (TB) is one of the world's leading causes of death due to infection and efforts to control TB would be substantially aided by the availability of an improved TB vaccine. There are currently nine new TB vaccines in clinical development, and the first efficacy trials are due to commence in 2009. There are many complex ethical issues which arise at all stages of TB vaccine development, from the need to conduct trials in developing countries to informed consent and the process of ethical review. While it is important that these issues are discussed, it may also be timely to consider the challenges which may arise if a vaccine in clinical development proves to be highly effective. We examine a number of scenarios where decisions on the deployment of a new TB vaccine may impact on the rights and liberty of the individual. © The Author(s) 2009.
first_indexed 2024-03-07T01:32:16Z
format Journal article
id oxford-uuid:93fdbc8a-f8b0-4b91-b5d7-6380bbc0e516
institution University of Oxford
language English
last_indexed 2024-03-07T01:32:16Z
publishDate 2009
record_format dspace
spelling oxford-uuid:93fdbc8a-f8b0-4b91-b5d7-6380bbc0e5162022-03-26T23:36:09ZA New Vaccine for Tuberculosis: The Challenges of Development and DeploymentJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:93fdbc8a-f8b0-4b91-b5d7-6380bbc0e516EnglishSymplectic Elements at Oxford2009Fletcher, HHawkridge, TMcshane, HTuberculosis (TB) is one of the world's leading causes of death due to infection and efforts to control TB would be substantially aided by the availability of an improved TB vaccine. There are currently nine new TB vaccines in clinical development, and the first efficacy trials are due to commence in 2009. There are many complex ethical issues which arise at all stages of TB vaccine development, from the need to conduct trials in developing countries to informed consent and the process of ethical review. While it is important that these issues are discussed, it may also be timely to consider the challenges which may arise if a vaccine in clinical development proves to be highly effective. We examine a number of scenarios where decisions on the deployment of a new TB vaccine may impact on the rights and liberty of the individual. © The Author(s) 2009.
spellingShingle Fletcher, H
Hawkridge, T
Mcshane, H
A New Vaccine for Tuberculosis: The Challenges of Development and Deployment
title A New Vaccine for Tuberculosis: The Challenges of Development and Deployment
title_full A New Vaccine for Tuberculosis: The Challenges of Development and Deployment
title_fullStr A New Vaccine for Tuberculosis: The Challenges of Development and Deployment
title_full_unstemmed A New Vaccine for Tuberculosis: The Challenges of Development and Deployment
title_short A New Vaccine for Tuberculosis: The Challenges of Development and Deployment
title_sort new vaccine for tuberculosis the challenges of development and deployment
work_keys_str_mv AT fletcherh anewvaccinefortuberculosisthechallengesofdevelopmentanddeployment
AT hawkridget anewvaccinefortuberculosisthechallengesofdevelopmentanddeployment
AT mcshaneh anewvaccinefortuberculosisthechallengesofdevelopmentanddeployment
AT fletcherh newvaccinefortuberculosisthechallengesofdevelopmentanddeployment
AT hawkridget newvaccinefortuberculosisthechallengesofdevelopmentanddeployment
AT mcshaneh newvaccinefortuberculosisthechallengesofdevelopmentanddeployment