HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers

Rabbits and monkeys immunized with HIV type 1 (HIV-1) native-like BG505 SOSIP.664 (BG505s) glycoprotein trimers are known to induce antibodies that can neutralize the autologous tier-2 virus. Here, we assessed the induction of HIV-1 trimer binding and neutralizing antibody (nAb) titres when BG505s t...

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Bibliographic Details
Main Authors: Capucci, S, Wee, E, Schiffner, T, LaBranche, C, Borthwick, N, Cupo, A, Dodd, J, Dean, H, Sattentau, Q, Montefiori, D, Klasse, P, Sanders, R, Moore, J, Hanke, T
Format: Journal article
Language:English
Published: Public Library of Science 2017